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Protocol version/date 200131Protocol in Makeup Ischemic Stroke Trial (TWIST) A randomisedcontrolled trial of thrombolytic treatment with for acute ischemic stroke upon awakening Extract number: 201400009680
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Immediately call emergency services or go to the nearest hospital.
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Provide information about the time when the symptoms started.
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Do not give the person anything to eat or drink.
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Follow the doctor's instructions for treatment.

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Anyone who experiences symptoms of a wake-up ischemic stroke such as sudden numbness or weakness in the face, arm, or leg, especially on one side of the body.
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Individuals who have risk factors for stroke such as high blood pressure, diabetes, smoking, or a history of previous strokes.
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In wake-up ischemic stroke, patients experience stroke symptoms upon waking up or at an unknown time.
Healthcare professionals and medical facilities are required to report cases of wake-up ischemic stroke.
Healthcare professionals should document the patient's symptoms, medical history, and perform necessary tests to confirm the diagnosis.
The purpose of reporting in wake-up ischemic stroke is to track and monitor cases for research and treatment purposes.
Information such as patient demographics, symptoms, time of onset, treatment provided, and outcome must be reported in wake-up ischemic stroke cases.
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