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AD Award Number:DAMD179717088TITLE: Clonal Hematopoiesis as a Marker of Genetic Damage Following Adjuvant Chemotherapy for Breast Cancer: Pilot Study to Evaluate IncidencePRINCIPAL INVESTIGATOR:CONTRACTING
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01
Obtain a blood sample from the individual.
02
Isolate DNA from the blood sample.
03
Perform targeted sequencing or deep sequencing to identify clonal hematopoiesis mutations.
04
Analyze the sequencing data to determine the presence and frequency of clonal hematopoiesis mutations.
05
Interpret the results in the context of the individual's medical history and clinical presentation.

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Individuals with a history of cancer or certain genetic predispositions may benefit from testing for clonal hematopoiesis as it can provide insight into their risk of developing hematological malignancies.
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Clonal hematopoiesis is a condition where there is an increased production of blood cells from a single abnormal stem cell.
Patients diagnosed with clonal hematopoiesis are required to report it to their healthcare providers.
Clonal hematopoiesis can be reported by providing a detailed medical history and undergoing specific blood tests.
The purpose of reporting clonal hematopoiesis is to monitor the progression of the condition and assess the risk of developing blood cancers.
Information such as the type of mutation present, blood cell counts, and any associated symptoms should be reported.
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