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Institute Report No. 27900
Dermal Sensitization Potential of
Nitrosamine in Guinea PigsDenzil F. Frost, MIS, DVM, CPT, VC
Gary M. Dacha, DVA, CPT, VC
Robert E. Harris, DVM, CPT, VC
C. Dale Smith,
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How to fill out dermal sensitization potential of
How to fill out dermal sensitization potential of
01
Obtain all relevant information on the test substance.
02
Choose an appropriate test method such as the Local Lymph Node Assay (LLNA) or the Guinea Pig Maximization Test (GPMT).
03
Prepare the test substance for application on the skin of the test animal.
04
Apply the test substance to the skin of the test animal according to the chosen test method and schedule.
05
Observe and record any signs of sensitization reaction on the test animal.
06
Analyze the results and determine the dermal sensitization potential of the test substance.
Who needs dermal sensitization potential of?
01
Researchers developing new chemicals or products that may come into contact with human skin.
02
Regulatory authorities evaluating the safety of chemicals for use in consumer products.
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What is dermal sensitization potential of?
Dermal sensitization potential refers to the ability of a substance to cause an allergic reaction when it comes into contact with the skin.
Who is required to file dermal sensitization potential of?
Companies and manufacturers who produce or use substances that may have dermal sensitization potential are required to file this information.
How to fill out dermal sensitization potential of?
The dermal sensitization potential of a substance can be filled out by providing relevant information on the substance's potential to cause skin allergies, along with any known methods of prevention or mitigation.
What is the purpose of dermal sensitization potential of?
The purpose of reporting dermal sensitization potential is to ensure the safety of workers and consumers who may be exposed to substances that can cause skin allergies.
What information must be reported on dermal sensitization potential of?
Information such as the substance's chemical composition, potential to cause allergic reactions, and recommended safety measures must be reported on the dermal sensitization potential form.
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