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Get the free BCR/ABL gene fusion detection kit (ES) Instructions Manual

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Wuhan Healthcare Biotechnology Co., Ltd. Floor 14, Building #8, Optics Valley Precision Medicine Industry Base Phase I, #9 Gaëtan 3rd Road, East Lake Fifth Zone, Wuhan City, Hubei Province, People\'s
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01
Collect the blood sample from the patient.
02
Isolate the RNA from the blood sample using a suitable method.
03
Perform reverse transcription to convert RNA into cDNA.
04
Amplify the cDNA using polymerase chain reaction (PCR) with specific primers for bcrabl gene fusion detection.
05
Analyze the PCR products using gel electrophoresis or another suitable method to detect bcrabl gene fusion.

Who needs bcrabl gene fusion detection?

01
Patients suspected of having chronic myelogenous leukemia (CML).
02
Patients with a history of exposure to chemicals or radiation that may increase the risk of developing CML.
03
Patients who have relatives with CML or a known genetic predisposition to the disease.
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BCR-ABL gene fusion detection is a laboratory test used to identify the presence of a specific genetic fusion between the BCR gene on chromosome 22 and the ABL gene on chromosome 9, which is associated with certain types of leukemia, particularly chronic myeloid leukemia (CML).
Patients suspected of having chronic myeloid leukemia (CML) or other related blood disorders are typically required to undergo BCR-ABL gene fusion detection as part of their diagnostic process.
Filling out BCR-ABL gene fusion detection typically involves providing the patient's medical history, consent for genetic testing, and submitting samples (usually blood or bone marrow) to a designated laboratory for analysis.
The purpose of BCR-ABL gene fusion detection is to confirm the diagnosis of chronic myeloid leukemia (CML) and to guide treatment decisions by determining the presence and quantity of the BCR-ABL fusion gene.
Reports of BCR-ABL gene fusion detection must include the presence or absence of the fusion gene, the type of fusion detected, quantification of the fusion gene, and any recommendations for further testing or treatment.
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