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M I RO OPEN VERSUS LAPAROSCOPICALLYASSISTED ESOPHAGECTOMY FOR CANCER: A multi center Phase III prospective randomized controlled trial PRC 2008 AFSSA PS Registration number: 2009A0014453L\'or dell\'azzuroJoan
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Step 1: Determine the research question or hypothesis that you want to investigate.
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Step 2: Design the study protocol, specifying the objectives, methods, and endpoints.
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Step 3: Identify potential participating centres or institutions and establish collaborations.
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Step 4: Obtain ethical approval from relevant authorities.
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Step 5: Develop a detailed data collection plan and randomization procedure.
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Step 6: Train study personnel on the study protocol and data collection procedures.
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Step 7: Recruit eligible participants from different centres and obtain informed consent.
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Step 8: Randomize participants into different treatment groups.
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Step 9: Implement the interventions or treatments as per the study protocol.
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Step 10: Collect and record data according to the predefined endpoints and time points.
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Step 11: Analyze the data using appropriate statistical methods.
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Step 12: Interpret the results and draw conclusions based on the findings.
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Step 13: Communicate the study findings through scientific publications or presentations.

Who needs a multicentre randomised controlled?

01
Researchers and scientists conducting clinical trials or intervention studies.
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Policy makers and healthcare administrators making decisions about healthcare interventions.
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Patients and the general public who benefit from evidence-based healthcare practices.

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A multicentre randomised controlled trial (RCT) is a study conducted across multiple locations to evaluate the effectiveness of a treatment or intervention by randomly assigning participants to either the treatment group or the control group.
Typically, researchers or institutions conducting the study are required to file a multicentre randomised controlled, including academic institutions, pharmaceutical companies, and clinical research organizations.
Filling out a multicentre randomised controlled involves completing specific application forms as required by regulatory authorities, including providing details about the study design, participant recruitment, ethical considerations, and expected outcomes.
The purpose of a multicentre randomised controlled trial is to generate high-quality evidence about the effectiveness and safety of a treatment or intervention across diverse populations and settings.
Information must include study objectives, methodology, participant eligibility criteria, recruitment strategies, data collection methods, statistical analysis plans, and the anticipated timeline.
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