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AD Award Number: DAMD179919447TITLE: Regulation of Cmyc Gene Expression by Potassium Channel Blocker Quindine in MCF7 Human Breast Cancer Cell LinePRINCIPAL INVESTIGATOR: Zaroui Melkoumian, B.S.CONTRACTING
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How to fill out regulation of c-myc gene
How to fill out regulation of c-myc gene
01
Start by gathering all the necessary information and materials related to the regulation of the c-myc gene.
02
Begin by identifying the specific regulatory elements and factors involved in controlling the expression of the c-myc gene.
03
Analyze the DNA sequence of the c-myc gene and identify any relevant binding sites for regulatory factors.
04
Use techniques such as electrophoretic mobility shift assays (EMSAs) to study the interaction between regulatory factors and the c-myc gene.
05
Investigate the role of chromatin remodeling and modifications in the regulation of the c-myc gene.
06
Study the effect of transcription factors and signaling pathways on the expression of the c-myc gene.
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Determine the mechanisms by which different regulatory elements and factors influence the activity of the c-myc gene.
08
Analyze the impact of mutations or genetic alterations on the regulation of the c-myc gene.
09
Validate the findings through experimental approaches such as reporter gene assays or knockout models.
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Summarize and interpret the results to gain a comprehensive understanding of the regulation of the c-myc gene.
Who needs regulation of c-myc gene?
01
Cancer researchers studying the development and progression of cancer.
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Pharmaceutical companies developing targeted therapies for cancer treatment.
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Geneticists interested in understanding gene regulation and its implications.
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Medical professionals aiming to diagnose and treat diseases related to aberrant c-myc gene expression.
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Biotechnology companies involved in genetic engineering and manipulation of gene expression.
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What is regulation of c-myc gene?
The regulation of the c-myc gene refers to the mechanisms that control the expression of the c-myc oncogene, which plays a crucial role in cell cycle progression, cellular growth, and apoptosis.
Who is required to file regulation of c-myc gene?
Researchers and institutions conducting studies that involve the c-myc gene must file regulations related to its research and usage.
How to fill out regulation of c-myc gene?
Filling out regulation of the c-myc gene typically involves submitting research protocols, compliance documents, and any relevant data to oversight boards or authorities.
What is the purpose of regulation of c-myc gene?
The purpose of regulating the c-myc gene is to ensure that research involving this oncogene is conducted ethically, safely, and in compliance with scientific and legal guidelines.
What information must be reported on regulation of c-myc gene?
Information that must be reported includes the research objectives, methodologies, potential impacts on health and safety, and any ethical considerations associated with the study.
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