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Chapman University Chapman University Digital Commons Pharmaceutical Sciences (MS) ThesesDissertations and Thessaly 122022Role of Macrophages in Ocular Surface Fibrosis Ayanna Corpus Chapman University,
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Macrophages are immune cells that play a crucial role in the body's defense against infections and diseases.
03
They are derived from monocytes and are present in various tissues throughout the body.
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Macrophages have multiple functions, including phagocytosis, antigen presentation, and cytokine production.
05
Phagocytosis is the process of engulfing and destroying foreign particles, such as bacteria, viruses, and dead cellular debris.
06
Macrophages also play a key role in initiating and coordinating the immune response by presenting antigens to other immune cells, such as T cells.
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Furthermore, macrophages produce cytokines, which are signaling molecules that regulate inflammation, immune cell activation, and tissue repair.
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Understanding the intricate role of macrophages in immune responses is essential for developing therapeutic approaches for various diseases like infections, autoimmune disorders, and cancer.
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Researchers study macrophages in both in vitro and in vivo models to uncover their specific functions in different contexts.
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Advances in immunology research continue to provide insights into the role of macrophages, leading to the development of targeted therapies.

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- Patients with infections, where macrophages help in clearing the invading pathogens.
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- Individuals with cancer, as macrophages can have both pro-tumor and anti-tumor effects depending on the context.
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- Researchers and scientists studying immunology and developing new therapies targeting macrophages.
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- Anyone interested in understanding the complex immune system and its components, including macrophages.
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Macrophages play a crucial role in the immune system by identifying, engulfing, and destroying pathogens and dead cells, as well as facilitating tissue repair and modulating immune responses.
Researchers, scientists, and healthcare professionals engaged in immunology and related fields may be required to document the role of macrophages in their studies, publications, or regulatory filings.
To fill out information regarding the role of macrophages, one would typically need to provide details on their biological functions, mechanisms of action, and any relevant data from experiments or clinical studies.
The purpose of documenting the role of macrophages is to enhance understanding of immune responses, aid in disease research, and support the development of therapies targeting immune system functions.
Researchers should report data including macrophage types, their functions, interactions with other immune cells, and any experimental results that highlight their role in health and disease.
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