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Appendix A: Supplementary Tables and Figures Table 1: Inpatient Internal MicroDosing Protocol (n25 responses) Status of site\'s inpatient internal microdosing protocolNumber of responses (%)aThere
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01
Start with a low dosage: Begin with a very small amount of psilocybin mushrooms, usually around 0.1 grams.
02
Create a schedule: Decide on a schedule for microdosing, usually every three days. Stick to this schedule consistently.
03
Use a scale: Use a precise scale to measure the dosage accurately. It is crucial to be consistent with the amount taken.
04
Consume the mushrooms: Either eat the mushrooms directly or incorporate them into food or drinks.
05
Maintain a journal: Keep a record of the dosage, effects, and any other observations after each microdosing session.
06
Observe effects: Pay attention to how you feel after taking the mushrooms. Note any changes in mood, cognition, or overall well-being.
07
Adjust dosage if necessary: If the effects are too strong or too weak, adjust the dosage slightly for the next session.
08
Mindset and setting: Ensure you are in a safe and comfortable environment when microdosing. Set intentions and have a positive mindset.
09
Seek professional guidance: If unsure or if you have specific medical conditions, consult a qualified professional before starting microdosing.
10
Be mindful of legality: Understand the legal status of psilocybin mushrooms in your jurisdiction and act accordingly.

Who needs microdosing with psilocybin mushrooms?

01
Individuals seeking personal growth and self-improvement: Microdosing with psilocybin mushrooms has been reported to enhance creativity, problem-solving abilities, mood, and overall well-being.
02
Those with mental health conditions: Some individuals with depression, anxiety, or other mental health conditions have reported positive effects from microdosing. However, it is essential to consult a professional before attempting microdosing as a treatment.
03
Individuals looking for alternative therapies: Microdosing may be appealing to individuals who prefer non-traditional approaches to wellness and mental well-being.
04
Researchers and scientists: Microdosing experiments are being conducted to study the potential benefits and effects of psilocybin mushrooms on cognition, mood, and neuroplasticity.
05
Curious individuals: Some people may be interested in exploring the effects of microdosing with psilocybin mushrooms out of curiosity or to gain insight into their own mind and consciousness.

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Microdosing with psilocybin mushrooms involves taking sub-perceptual doses of psilocybin, the active compound in certain mushrooms, typically for enhancing cognitive function, creativity, and emotional balance without experiencing full psychedelic effects.
Individuals who are participating in regulated studies or programs related to psilocybin use may be required to file reports or documentation regarding their microdosing practices.
To fill out documentation related to microdosing with psilocybin mushrooms, individuals typically need to provide details such as dosage, frequency of use, subjective effects, and any observed changes in mental or physical health.
The purpose of microdosing with psilocybin mushrooms is to potentially enhance well-being, improve mood, increase creativity, and reduce anxiety or depression, while avoiding the intense effects associated with full doses.
Information that must be reported typically includes the amount of psilocybin consumed, duration and frequency of microdosing, any side effects experienced, and overall impacts on daily functioning.
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