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Antiepidermal growthfactor receptor (EGFR) monoclonal antibody (MoAb) treatment for chemotherapy refractory or metastatic colorectal cancer has obtained great achievement. However, not every colorectal
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Mechanisms of resistance refer to the ways in which organisms, often pathogens or pests, adapt to evade or survive the effects of treatment methods, such as antibiotics or pesticides.
Researchers, healthcare providers, and companies using antimicrobial agents or pesticides are typically required to file mechanisms of resistance to regulatory authorities.
To fill out mechanisms of resistance, individuals should follow the specific guidelines provided by the regulatory body, including detailing the organism, the resistance observed, the methods used for testing, and any supporting data.
The purpose of mechanisms of resistance is to monitor and manage the emergence of resistance trends, inform treatment options, ensure public health safety, and guide policy for antibiotic and pesticide use.
Information that must be reported includes the species involved, the specific resistance mechanisms identified, testing methods used, results obtained, and any relevant epidemiological data.
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