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Journal of Experimental Botany, Vol. 66, No. 18 pp. 56055615, 2015 doi:10.1093/jxb/erv100 Advance Access publication 20 March 2015 This paper is available online free of all access charges (see http://jxb.oxfordjournals.org/open_access.html

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Define the research question or hypothesis.

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What is genome-wide association study of?

A genome-wide association study (GWAS) is a research approach used to identify genetic variants associated with diseases or traits by examining the genomes of many individuals.

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Researchers conducting genome-wide association studies involving human subjects or genetic data are typically required to file relevant documentation, including institutional review boards and ethical boards.

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To fill out a genome-wide association study, researchers must collect and analyze genetic data from a large cohort, then use statistical methods to identify associations between genetic variants and traits or diseases.

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The purpose of a genome-wide association study is to identify and understand the genetic factors that contribute to human diseases and traits, ultimately guiding medical research and potential treatments.

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Information that must be reported generally includes the study design, participant demographics, genetic variant associations, statistical analyses, and any findings related to the traits or diseases studied.

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