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How to expand access refers to the processes and guidelines established to increase patient access to investigational medical treatments, particularly those that have not yet been approved by regulatory authorities.
Sponsors of investigational drugs or devices that seek to provide access to patients outside of clinical trials are required to file for expanded access.
To fill out a request for expanded access, sponsors need to complete specific forms provided by regulatory agencies, including detailed information about the product, the patient population, the rationale for access, and a plan for monitoring.
The purpose of how to expand access is to provide patients with serious or life-threatening conditions the opportunity to receive experimental treatments that may not yet be commercially available.
Information that must be reported includes patient identifiers, treatment details, potential risks, informed consent, and outcomes of the treatment.
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