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Department of Physics, Chemistry and Biology (IFM)Masters ThesisInvestigation of hPin1 mediated phosphorylation dependency in degradation control of cMyc oncoprotein Malin Johansson September 2012
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What is in silico modeling of?
In silico modeling refers to the use of computer simulations and computational techniques to study and predict biological processes, drug interactions, and the behavior of molecules in a virtual environment.
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Researchers, pharmaceutical companies, and biotechnology firms developing new drugs or engaging in biological research are typically required to file in silico modeling results as part of regulatory submissions.
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To fill out in silico modeling submissions, one must provide details of the modeling approach, algorithms used, validation procedures, and relevant data sets, along with results and interpretations.
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The purpose of in silico modeling is to enhance understanding of biological systems, expedite drug discovery processes, reduce research costs, and predict the efficacy and safety of compounds before clinical trials.
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The report on in silico modeling should include the modeled systems, parameters, software and algorithms used, validation data, outcomes, and any assumptions made during modeling.
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