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Nontargeted analysis of placentas from preeclamptic patients identifies links to acetaminophen and molecular alterations relevant to cell deathCeleste CarberryHonors Thesis ENHS Department of Environmental
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01
Collect placenta samples by removing the membranes and cutting small pieces.
02
Wash the samples with a sterile saline solution to remove excess blood.
03
Homogenize the samples to create a uniform mixture.
04
Extract metabolites using an appropriate solvent extraction method.
05
Analyze the extracted metabolites using techniques such as mass spectrometry or nuclear magnetic resonance.
06
Compare the results with a database of known metabolites to identify any abnormalities or biomarkers.

Who needs non-targeted analysis of placentas?

01
Researchers studying placental function and metabolism.
02
Healthcare professionals investigating pregnancy complications.
03
Developers of new diagnostic tools for prenatal health.
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Non-targeted analysis of placentas refers to a comprehensive examination of placental tissue that does not focus on specific known parameters or biomarkers. This type of analysis aims to identify a wide range of physiological or pathological conditions and can reveal unexpected findings that may contribute to understanding placental function and its impact on pregnancy outcomes.
Typically, healthcare providers, researchers, or institutions involved in placenta research or clinical studies may be required to file non-targeted analysis of placentas. Specific regulations or guidelines may vary by region or institution.
To fill out a non-targeted analysis of placentas, one should gather all relevant data regarding the sample, including the patient's information, clinical background, methodology used for analysis, results, and any interpretations or conclusions drawn. Following institutional or regulatory guidelines for reporting is essential.
The purpose of non-targeted analysis of placentas is to gain insights into placental structure and function, identify potential abnormalities, and understand their implications for maternal and fetal health. This analysis can lead to new discoveries in reproductive biology and inform clinical practice.
Information that must be reported on non-targeted analysis of placentas includes sample identification, clinical history, analysis methods, findings, and any relevant demographic details. It is important to include interpretations and potential clinical implications.
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