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Centers for Medicare & Medicaid Services Center for Medicare and Medicaid Innovation Seamless Care Models Group (SCMG) 7500 Security Boulevard Baltimore, MD 21244Cell and Gene Therapy (CGT) Access
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Who needs cell and gene formrapies?

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Patients suffering from genetic disorders.
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Individuals with certain types of cancer.
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People with autoimmune diseases.
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Those in need of regenerative therapies.
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Cell and gene therapies are innovative medical treatments that involve modifying or manipulating cells or genes to treat or prevent diseases, often targeting genetic disorders or cancers.
Companies and organizations that develop, manufacture, or distribute cell and gene therapies are required to file cell and gene formrapies with regulatory authorities.
Filing cell and gene formrapies typically involves completing specific regulatory forms provided by the relevant authority, detailing the therapy's characteristics, intended use, safety, and efficacy data.
The purpose of filing cell and gene formrapies is to ensure the safety and efficacy of these therapies before they are approved for use in patients.
Required reporting information includes the therapy's composition, manufacturing process, preclinical and clinical trial results, proposed labeling, and any potential risks and benefits.
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