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FoundationOneCDx Technical Information Foundation Medicine, Inc. 150 Second Street, Cambridge, MA 02141 Phone: 617.418.2200 Intended Use FoundationOneCDx (F1CDx) is a next generation sequencing based

How to fill out egfrexon 20 insertion mutation

How to fill out egfrexon 20 insertion mutation

1. Select the appropriate sample for testing.
2. Prepare the sample according to the testing protocol.
3. Perform the PCR amplification reaction with specific primers to target the EGFR exon 20 region.
4. Analyze the PCR products using sequencing techniques to identify any mutations in the EGFR exon 20 insertion.

Who needs egfrexon 20 insertion mutation?

1. Patients with non-small cell lung cancer who have been identified as potentially benefiting from EGFR exon 20 insertion mutation targeted therapies.
2. Researchers studying the molecular mechanisms and targeted treatments for EGFR exon 20 insertion mutations in cancer.

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What is egfrexon 20 insertion mutation?

The egfrexon 20 insertion mutation refers to a specific genetic alteration where an insertion occurs in the EGFR (epidermal growth factor receptor) gene at the 20th amino acid position, which can affect cellular signaling and may be involved in certain types of cancers, particularly non-small cell lung cancer.

Who is required to file egfrexon 20 insertion mutation?

Individuals or organizations, such as clinical laboratories or healthcare providers, that conduct genetic testing related to EGFR mutations in patients, particularly those diagnosing or treating cancer, are typically required to report the egfrexon 20 insertion mutation.

How to fill out egfrexon 20 insertion mutation?

Filling out the egfrexon 20 insertion mutation report involves documenting patient identification details, test results, the specific mutation identified, and necessary clinical information as per regulatory guidelines and institutional protocols.

What is the purpose of egfrexon 20 insertion mutation?

The purpose of identifying the egfrexon 20 insertion mutation is to provide information on the genetic makeup of a patient's tumor, which can inform treatment options, such as targeted therapies, and help predict the potential response to specific cancer treatments.

What information must be reported on egfrexon 20 insertion mutation?

The report on egfrexon 20 insertion mutation must include patient demographics, testing methodology, details of the mutation, clinical relevance, interpretation of the results, and recommendations for treatment if applicable.