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Translational Oncology 13 (2020) 100799Contents lists available at ScienceDirectTranslational Oncology journal homepage: www.elsevier.com/locate/tranonAdvanced Cancer Patient Knowledge of and Attitudes

How to fill out genomic profiling of circulating

How to fill out genomic profiling of circulating

1. Obtain a blood sample from the patient following standard procedures.
2. Process the blood sample to separate plasma from cellular components.
3. Extract circulating tumor DNA (ctDNA) from the plasma using a reliable extraction method.
4. Quantify the amount of ctDNA to ensure sufficient quantity for analysis.
5. Select appropriate genomic profiling technology (e.g., NGS, PCR) based on the clinical question.
6. Prepare the ctDNA sample according to the specifications of the chosen profiling technology.
7. Conduct the genomic profiling assay, ensuring quality control measures are in place.
8. Analyze the results and interpret the genomic mutations or alterations identified.
9. Discuss the findings with the healthcare team and determine suitable treatment options.

Who needs genomic profiling of circulating?

1. Patients with advanced cancer needing personalized treatment options.
2. Individuals with treatment-resistant cancers to identify potential new therapies.
3. Patients enrolled in clinical trials requiring genetic profiling for eligibility.
4. Those with a family history of cancer to assess hereditary mutations.
5. Patients experiencing disease progression to evaluate new genomic insights.

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What is genomic profiling of circulating?

Genomic profiling of circulating refers to the analysis of genetic material found in bodily fluids, such as blood, to identify mutations or alterations in genes that can inform treatment decisions, particularly in cancer therapy.

Who is required to file genomic profiling of circulating?

Healthcare providers and laboratories that perform genomic profiling tests on patients are typically required to file genomic profiling of circulating.

How to fill out genomic profiling of circulating?

To fill out genomic profiling of circulating, healthcare providers must collect patient information, specify the type of test conducted, and provide results in a standardized format as per regulatory guidelines.

What is the purpose of genomic profiling of circulating?

The purpose of genomic profiling of circulating is to evaluate the genetic changes in a patient’s tumor, guide personalized treatment options, and monitor disease progression or response to therapy.

What information must be reported on genomic profiling of circulating?

Information that must be reported includes patient demographics, details of the genomic tests performed, results of the analysis, and interpretation of findings.