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UNIVERSITY OF CALIFORNIA SANTA CRUZ Mechanistic studies using a humanized yeast strain sensitive to splicing inhibitors A dissertation submitted in partial satisfaction of the requirements for the
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Broad variation in response refers to a framework or guideline that allows for a wide range of individual differences in the responses to a particular stimulus or treatment.
Individuals or entities that are part of a regulated system or industry that requires reporting on variability in responses, such as pharmaceutical companies, must file broad variation in response.
To fill out a broad variation in response, one must gather relevant data, follow the specific guidelines provided by the regulatory body, and accurately report the variability observed in the responses according to the prescribed format.
The purpose of broad variation in response is to ensure that variability in individual responses is documented and understood, which can inform better decision-making, product development, and regulatory compliance.
Information that must be reported includes the data on responses observed, the context of the study, demographic information, and any factors that may influence variability.
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