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UNIVERSITY OF CALIFORNIA SAN DIEGO Accumulation of Synuclein Impairs Trafficking and Processing of Amyloid Precursor Protein in a Mouse Model of Parkinsons Disease A Thesis submitted in partial satisfaction
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The accumulation of -synuclein impairs neuronal function and contributes to neurodegenerative diseases such as Parkinson's disease by disrupting synaptic communication and promoting cell death.
Typically, researchers, healthcare professionals, or organizations studying or treating neurodegenerative diseases may be required to document the accumulation of -synuclein.
Filling out the documentation involves compiling data from laboratory tests, clinical evaluations, and research findings related to -synuclein levels, along with detailed descriptions of methodologies used.
The purpose is to better understand the implications of -synuclein accumulation in disease processes, to facilitate diagnosis, and to aid in the development of therapeutic interventions.
Reported information typically includes clinical symptoms, imaging and biochemical data, the methodologies used for analysis, and any therapeutic implications derived from the findings.
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