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This dissertation presents a genome-wide investigation into the direct substrates of nonsense-mediated mRNA decay (NMD) in the model organism Caenorhabditis elegans. It identifies and characterizes mRNA transcripts that are specifically targeted and degraded by the NMD pathway, highlighting the biological significance of NMD in regulating gene expression and identifying novel substrates including alternatively spliced mRNA, pseudogenes, and specific gene families. Findings suggest a role for...
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What is global characterization of form?
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