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This document outlines the protocol for a clinical trial designed to determine the efficacy and safety of recombinant human alkaline phosphatase (recAP) in patients with sepsis-associated acute kidney injury (SA-AKI). The trial is structured as a randomized, double-blind, placebo-controlled study across multiple centers, with a focus on mortality and kidney function as primary endpoints. The study aims to evaluate the impact of recAP on patient outcomes compared to placebo over a specified...
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