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This review explores the role of PKMζ, an atypical PKC isoform, in stress response and depression. It discusses how excessive stress leads to maladaptive changes in the stress system, contributing to depression, and highlights the involvement of PKMζ in memory maintenance and its potential as a molecular target for developing new antidepressants. The review provides insights into the complex relationship between stress, depression, and synaptic plasticity mediated by PKMζ in various brain...
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Involvement of PKM refers to the participation or engagement of individuals or entities in the processes, activities, or responsibilities related to project or program management within an organization.
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Reported information usually includes participant names, roles, project details, duration of involvement, contributions made, and any outcomes or impact assessments.
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