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Safety Data Sheet SDS created:201120191 Identification of substance and manufacturer Axon catalogue ID 3042 Product name AZD6280 IUPAC name 4Amino8(2,5dimethoxyphenyl)Npropylcinnoline3carboxamideCAS
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01
Start with a basic understanding of the GABAA receptor structure.
02
Identify the main components: alpha, beta, and gamma subunits.
03
Map out the location of the binding sites for GABA and other modulators.
04
Detail the structural features like transmembrane domains and extracellular loops.
05
Indicate the arrangement of the subunits in the pentameric structure.
06
Use diagrams to illustrate the 3D conformation of the receptor.
07
Include data or references to crystal structures if available.

Who needs gabaa receptors structure and?

01
Neuroscientists researching neurotransmitter systems.
02
Pharmacologists developing drugs targeting GABAA receptors.
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Medical professionals studying disorders related to GABAergic activity.
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Students and educators in neuroscience courses.
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Biologists interested in receptor biology and signaling.
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GABA_A receptors are ionotropic receptors composed of five subunits that form a central ion channel. These receptors mediate fast inhibitory neurotransmission in the brain.
Researchers and institutions conducting studies that involve GABA_A receptor structures are typically required to file relevant data regarding their findings.
To fill out the GABA_A receptors structure, ensure you accurately report the receptor composition, experimental methods used, and any relevant findings regarding its functionality.
The purpose of filing GABA_A receptor structure information is to enhance scientific understanding, promote data sharing, and facilitate future research in neuropharmacology and related fields.
Information required includes the specific subunit arrangement, binding sites, structural data, and functional assays demonstrating the receptor's activity.
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