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This article reviews the genetic architecture of ADHD (Attention-deficit/hyperactivity disorder) and its comorbidity with other psychiatric disorders, discussing the genetic correlations, molecular mechanisms, and implications for treatment. It summarizes findings from genome-wide association studies (GWAS) and quantitative genetic studies, highlighting the role of shared genetic factors in ADHD and related traits.
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The genetic architecture of ADHD refers to the underlying genetic factors and their interactions that contribute to the development and manifestation of Attention-Deficit/Hyperactivity Disorder. This includes various genes, their variants, and how they influence neurodevelopmental processes.
Researchers and medical professionals studying ADHD genetics, as well as institutions involved in ADHD-related genetic research, may be required to file genetic architecture data for regulatory or funding purposes.
To fill out genetic architecture of ADHD, one must gather relevant genetic data, phenotype information, and any relevant research findings, then compile and format this information according to specific research or regulatory guidelines.
The purpose of understanding the genetic architecture of ADHD is to discover the genetic variants associated with the disorder, improve diagnostic criteria, inform treatment strategies, and enhance our understanding of its biological mechanisms.
Information on genetic variants, associated phenotypes, research methods, participant demographics, and analysis results must be reported on the genetic architecture of ADHD.
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