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University of GroningenBiological and pharmacological functions of the FGF19 and FGF21coreceptor beta klotho Aaldijk, Alexandra S.; Verzijl, Cristy R.C.; Jonker, Johan W.; Struik, Dicky Published
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Begin by identifying the biological functions relevant to the organism or system being studied.
02
Gather data on each biological function, including its mechanism, purpose, and interactions with other functions.
03
Research the pharmacological aspects, focusing on how specific drugs or compounds influence these biological functions.
04
Document the effects of various pharmacological agents on the biological functions identified, noting both positive and negative interactions.
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Organize the information in a clear manner, categorizing it by biological and pharmacological relevance.

Who needs biological and pharmacological functions?

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Biologists conducting research on organism functions.
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Pharmacologists involved in drug development and study.
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Biological functions refer to the roles and activities of a biological entity in an organism, including processes such as metabolism, reproduction, and cellular processes. Pharmacological functions involve the effects and mechanisms of action of drugs within biological systems, including therapeutic effects and side effects.
Entities involved in drug development, such as pharmaceutical companies, researchers, and healthcare providers, are required to file biological and pharmacological functions to regulatory bodies to ensure compliance with safety and efficacy standards.
To fill out biological and pharmacological functions, one must accurately document the relevant biological activities and effects of the drug, including experimental data, mechanisms of action, and any observed side effects, typically following guidelines set by regulatory agencies.
The purpose is to provide comprehensive data on the biological activities and pharmacological effects of a drug, ensuring it is safe and effective for human use while informing regulatory decisions.
The report must include details on the drug's mechanisms of action, biological pathways, effects on target organs, dose-response relationships, toxicity profiles, and any adverse effects observed during studies.
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