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This dissertation investigates the regulation of the Cdc25A phosphatase in human tumor cells, focusing on its interaction with cyclin-dependent kinase 2 (Cdk2). It explores how Cdc25A protein levels are maintained during the cell cycle, particularly during interphase and mitosis, highlighting its role as a cell cycle regulator and its overexpression in various cancers. The study reveals the molecular mechanisms underlying Cdc25A stability and turnover, including its phosphorylation by...
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01
Identify the specific conditions under which CDC25A regulation is necessary.
02
Gather necessary laboratory materials, including reagents and equipment.
03
Prepare cell cultures or organisms that will be used in the experiment.
04
Determine the methods for manipulating CDC25A activity, such as using inhibitors or RNA interference.
05
Conduct the experiment by applying the chosen method of regulation to the target cells or organisms.
06
Monitor the effects on cell cycle progression and any other phenotypic changes.
07
Analyze the data collected to assess the impact of the CDC25A regulation.

Who needs regulation of cdc25a in?

01
Researchers studying cell cycle regulation.
02
Scientists investigating cancer biology and therapeutic strategies.
03
Pharmaceutical companies developing drugs targeting cell cycle proteins.
04
Clinical laboratories performing assays related to cell proliferation.
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Regulation of cdc25a is involved in the control of the cell cycle, specifically in the transition between different phases by dephosphorylating cyclin-dependent kinases (CDKs).
Researchers and organizations involved in studies or activities concerning cell cycle regulation and related genetic or pharmacological research are required to file regulation of cdc25a.
To fill out regulation of cdc25a, provide details of the study or research, including objectives, methodology, results, and compliance with relevant guidelines.
The purpose of regulation of cdc25a is to ensure proper cell cycle progression and to prevent disorders related to uncontrolled cell growth, such as cancer.
Information that must be reported includes the purpose of the regulation, methodologies used, study results, and any compliance with legal or ethical guidelines.
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Relevant keywords

Cdc25A cyclin-dependent kinase 2 tumor cells cell cycle regulation phosphorylation ubiquitin ligase cell proliferation oncogenesis Cdk2 cancer research

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