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medRxiv preprint doi: https://doi.org/10.1101/2025.01.23.25321010; this version posted January 28, 2025. The copyright holder for this preprint (which was not certified by peer review) is the author/funder,
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Sex-specific metabolic signatures refer to distinct patterns of metabolites and metabolic processes that vary between male and female individuals, influencing health and disease states.
Researchers and clinicians conducting studies that involve the metabolic profiles of male and female subjects are typically required to file sex-specific metabolic signatures.
To fill out sex-specific metabolic signatures, one must collect data on metabolic profiles from both males and females, analyze the differences, and ensure all relevant metabolic markers are documented clearly.
The purpose of sex-specific metabolic signatures is to better understand how metabolic responses differ by sex, which can inform personalized medicine approaches and improve health outcomes.
Information that must be reported includes the identification of metabolites, their concentrations, the sex of the subjects, and any relevant physiological or pathological context.
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