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Imagine you were alive back in the 1980s, and were told that computers would soon take over everything: from shopping, to dating, and the stock market, that billions of people would be connected via a kind of web, that you would own a handheld device orders of magnitudes more powerful than supercomputers. It would seem absurd, but then all of it happened. Science fiction became our reality, and we don't even think about it. We're at a similar point today with genetic engineering. So let's talk about it. Where it came from, what we're doing right now, and about a recent breakthrough that will change how we live and what we perceive as normal forever. Humans have been engineering life for thousands of years. Through selective breeding, we strengthened useful traits in plants and animals. We became very good at this, but never fully understood how it worked. Until we discovered the code of life, Deoxyribonucleic Acid—DNA. A complex molecule that guides the growth, development, function, and reproduction of everything alive. Information is encoded in the structure of the molecule. Four nucleotides are paired and make up a code that carries instructions. Change the instructions, and you change the being carrying it. As soon as DNA was discovered, people tried to tinker with it. In the 1960s, scientist bombarded plants with radiation to cause random mutations in the genetic code. The idea was to get a useful plant variation by pure chance. Sometimes it actually worked too. In the 70s, scientists inserted DNA snippets into bacteria, plants, and animals to study and modify them for research, medicine, agriculture, and for fun. The earliest genetically modified animal was born in 1974, making mice a standard tool for research, saving millions of lives. In the 80s, we got commercial. The first patent was given for a microbe engineered to absorb oil. Today we produce many chemicals by means of engineered life, like life-saving clotting factors, growth hormones, and. All things we had to harvest from the organs of animals before that. The first food modified in the lab went on sale in 1994: the Flavor Save tomato, a tomato given a much longer shelf life where an extra gene that suppresses the build-up of a rotting enzyme. But GM food and the controversy surrounding them deserve a video of their own. In the 1990s, there was also a brief foray into human engineering. To treat maternal infertility, babies were made that carried genetic information from 3 humans. Making them the first humans ever to have 3 genetic parents. Today there are super muscled pigs, fast-growing salmon, featherless chicken, and see-through frogs. On the fun side, we made things glow in the dark. Fluorescent zebrafish are available for as little as ten dollars. All of this is already very impressive, but until recently gene editing was extremely expensive, complicated, and took a long time to do. This has now changed with a revolutionary new technology now entering the stage—CRISPR....
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