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Journal of Reviews in Medical Sciences. 2021; 1(2): e86 DOI: 10.22034/jrms.2021.366827.1011___Narrative Review Immunopathology of Multiple Sclerosis Melika Salari1, Niloofar alsadat Nourian2 1. Psychology Student, Payame Noor University of Kish International Center, Kish Island, Iran. 2. Graduated, Islamic Azad University, Najafabad Branch, Najafabad, Iran. Received: February 2021; Accepted: March 2021; Published online: April 2021Correspondence to: Niloofar alsadat Nourian, MD, Islamic Azad...
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Gather necessary clinical information and patient history.
02
Collect relevant tissue samples (e.g., brain or spinal cord biopsies).
03
Process the samples using appropriate immunohistochemical techniques.
04
Stain the tissue sections with specific antibodies to identify cellular components.
05
Analyze the stained samples under a microscope to assess inflammatory cell presence and patterns.
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Document the findings, noting the types of immune cells present and their distribution.
07
Correlate findings with clinical symptoms and diagnostic imaging.

Who needs immunopathology of multiple sclerosis?

01
Neurologists to aid in the diagnosis of multiple sclerosis.
02
Researchers studying the pathophysiology of multiple sclerosis.
03
Pathologists assessing tissue changes in neurological disorders.
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Healthcare providers involved in developing targeted therapies for multiple sclerosis patients.
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Immunopathology of multiple sclerosis refers to the study of the immune system's role in the disease, characterized by the attack on the myelin sheath of nerve fibers by autoreactive T cells and B cells, leading to inflammation and demyelination.
Typically, healthcare providers, especially neurologists and pathologists involved in diagnosing and treating multiple sclerosis, are required to document and file the immunopathological findings related to the disease.
To fill out the immunopathology of multiple sclerosis, include patient demographics, clinical history, imaging results, laboratory findings, and detailed descriptions of tissue pathology, including cellular infiltrates and myelin loss.
The purpose of immunopathology of multiple sclerosis is to understand the mechanisms of the disease, provide diagnostic information, guide treatment decisions, and contribute to research on therapeutic strategies.
Information that must be reported includes the type of immune cells present, the extent of demyelination, location of lesions, pathological features observed, and any relevant genetic or environmental risk factors.
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