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J. Agr. Sci. Tech. (2016) Vol. 18: 437452De Novo Characterization of the Root Transcriptome and Development of ESTSSR Markers in Paris polyphylla Smith var. yunnanensis, an Endangered Medical Plant
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De novo characterization refers to the process of defining and describing a product, particularly in the context of medical devices, that has not been previously classified by the FDA.
Any manufacturer or entity that seeks to market a novel medical device that does not have a predicate device and requires FDA clearance or approval is required to file for de novo characterization.
To fill out a de novo characterization, manufacturers must provide detailed information including device description, intended use, proposed labeling, and any data supporting the safety and effectiveness of the device.
The purpose of de novo characterization is to provide a regulatory pathway for novel medical devices that are low to moderate risk, allowing them to be classified in a manner that evaluates their safety and effectiveness.
Information that must be reported includes device specifications, indications for use, a summary of the technological characteristics, clinical data supporting safety and efficacy, and proposed labeling.
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