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antioxidants ReviewAlphaLipoic Acid: Biological Mechanisms and Health Benefits Fabiana Superti 1,2and Rosario Russo 3, * 123*Istituto Superiore di Sanit, Viale Regina Elena, 299, 00161 Rome, RM, Italy; fabiana.superti@iss.it or fabiana.superti@artoi.it Association for Research on Integrative Oncology Therapies, (ARTOI) Foundation, Via Ludovico Micara, 73, 00165 Rome, RM, Italy Giellepi S.p.A., Via G. Verdi, 41/Q, 20831 Seregno, MB, Italy Correspondence: rosario.russo@giellepi.itAbstract:
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Alpha-lipoic acid functions as an antioxidant, helps in mitochondrial energy production, and plays a role in glucose metabolism by regenerating other antioxidants.
Researchers, clinicians, or manufacturers involved in studies or applications related to alpha-lipoic acid may be required to file documentation regarding its biological mechanisms.
To fill out the biological mechanisms, one should collect relevant data from clinical studies, summarize the antioxidant properties, and describe the metabolic pathways influenced by alpha-lipoic acid.
The purpose is to understand how alpha-lipoic acid contributes to cellular functions, its potential therapeutic benefits, and its role in disease prevention.
The report should include mechanisms of action, dosages used in studies, effects observed in trials, and comparisons with other antioxidants.
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