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Filed pursuant to Rule 424(b)(3) Registration No. 333264083 SUPPLEMENT NO 1. DATED January 19, 2024 TO PROSPECTUS SUPPLEMENT DATED June 16, 2023 (To Prospectus Dated May 5, 2022)Edgewise Therapeutics,

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What is supplement no 1?

Supplement No. 1 is a specific form or document that typically provides additional information or supporting details in regulatory filings, often related to financial disclosures or compliance.

Who is required to file supplement no 1?

Entities or individuals that are required to provide additional details or supplementary information as part of their compliance with regulatory requirements or when submitting particular forms, often in financial or corporate contexts.

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To fill out Supplement No. 1, follow the provided instructions carefully, ensure all relevant information is accurate, complete all required sections, and double-check for consistency with primary filings before submission.

What is the purpose of supplement no 1?

The purpose of Supplement No. 1 is to provide supplementary details, clarify information, or disclose additional data that supports the primary filing, ensuring regulatory compliance and transparency.

What information must be reported on supplement no 1?

Supplement No. 1 typically requires information related to financial statements, additional disclosures, details of prior submissions, or any other relevant data that complements the main filing.

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