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Lima: Linear Models for Microarray Data User s Guide Gordon K. Smith, Matthew Ritchie, Natalie Thorne, James Whitehall and Wei Shi Bioinformatics Division, The Walter and Eliza Hall Institute of Medical
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Limma linear models are commonly used in bioinformatics for the analysis of gene expression data. They allow researchers to identify differentially expressed genes and compare gene expression levels between different experimental conditions.
Limma linear models are not something that needs to be filed. They are a statistical framework used for analyzing gene expression data in bioinformatics research and are not related to mandatory filings or legal requirements.
Limma linear models are implemented using specific software packages, such as the limma package in R. Researchers typically need to provide their gene expression data, experimental design information, and any covariates to the limma function in order to perform the analysis.
The purpose of limma linear models is to identify differentially expressed genes and compare gene expression levels between different experimental conditions. This statistical approach helps researchers understand the underlying biological processes and mechanisms related to gene expression changes.
Limma linear models do not require specific reporting in a formal sense. However, researchers typically report the significant genes, fold changes, p-values, and other statistical results obtained from the limma analysis in their research papers or publications.
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