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HIV-1 Subtype and Circulating Recombinant Form (CRF) Reference Sequences, 2005 Thomas Later, Bette Former, Marcus Daniels, Charles Calf, Brian Foley Los Alamos National Laboratory, Los Alamos, NM
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The HIV-1 subtype is a classification system used to categorize different strains of the Human Immunodeficiency Virus-1 (HIV-1) based on genetic variations.
Healthcare professionals and laboratories conducting HIV testing are required to report the HIV-1 subtype information to the relevant health authorities.
The HIV-1 subtype information can be filled out by conducting genetic sequencing of the viral samples obtained from HIV-positive individuals and comparing the genetic sequences to known subtype reference sequences.
The purpose of reporting the HIV-1 subtype is to monitor the spread of different strains of the virus and to understand their impact on disease progression, treatment effectiveness, and the development of vaccines.
The information reported on the HIV-1 subtype includes the specific subtype classification (e.g., subtype A, B, C, etc.), any circulating recombinant forms, drug resistance mutations, and other genetic variations.
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