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2013Add Health Wave IV
Documentation ReportCandidate Genes
Report prepared by
Andrew Stolen
Eric A. White
Joyce Tabor
La A. KilleyaJones
Carmen C. Culbertson
Jon M. Hussar
Carolyn T. Happen
Kathleen
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How to fill out candidate genes
How to fill out candidate genes:
01
Start by conducting a thorough literature review to identify potential candidate genes that may be relevant to the research question or area of interest.
02
Use databases such as NCBI Gene or Ensembl to search for known candidate genes associated with the specific phenotype or disease being studied.
03
Prioritize the candidate genes based on their biological relevance, previous evidence of association with the phenotype, or potential functional significance.
04
Gather information about the candidate genes, including gene symbol, gene name, chromosomal location, and any known genetic variations or mutations.
05
Perform data analysis to identify any gene expression patterns, protein-protein interactions, or pathway associations related to the candidate genes.
06
Validate the selected candidate genes using experimental techniques such as PCR, microarray analysis, or genetic association studies.
07
Document the findings and provide a detailed explanation of the rationale behind the selection of the candidate genes.
08
Review and update the list of candidate genes as new evidence or research emerges.
Who needs candidate genes:
01
Researchers working in the field of genetics or genomics who are studying the genetic basis of complex traits or diseases may need candidate genes.
02
Clinicians or medical professionals who are interested in understanding the genetic factors underlying certain diseases or disorders may also need candidate genes.
03
Pharmaceutical companies or drug developers may require candidate genes to identify potential therapeutic targets or biomarkers for drug development.
04
Agricultural researchers who are studying plant or animal breeding may use candidate genes to improve the selection of traits with desired genetic characteristics.
05
Forensic scientists or genetic counselors may utilize candidate genes to assess the risk of inherited diseases or to establish paternity in paternity testing.
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