Get the free Date of Report (date of earliest event reported): June 15, 2015

To identify which T cell co-stimulators enhance the efficacy of an allogeneic gp96-Ig secreting cell-based vaccine ImPACT we investigated the activity of agonistic antibodies targeting OX40 4-1BB and ICOS administered together with ImPACT. With a simpler cost structure than 1 1 n mAbs/biologics ComPACT DesignCombination Pan-Antigen Cytotoxic Therapy gp96-Ig Fc-OX40L Construct Prioritization Scheme There are multiple co-stimulatory receptors that may synergize with gp96-Ig based vaccines. CD8...

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