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01
Begin by collecting a sample of the patient's T cells through a process called leukapheresis.
02
Isolate and activate the T cells in the laboratory using specific growth factors and cytokines.
03
Introduce a viral vector containing the genetic information of a Chimeric Antigen Receptor (CAR) into the T cells.
04
Allow the T cells to express the CAR protein on their surface, which will enable them to recognize and bind to specific antigens on cancer cells.
05
Expand and culture the CAR T cells in the laboratory to generate a sufficient quantity for treatment.
06
Prior to infusion, the patient may undergo a conditioning regimen to prepare their immune system for the CAR T cell therapy.
07
Administer the CAR T cells to the patient through intravenous infusion.
08
Monitor the patient closely for any side effects or adverse reactions.
09
Assess the response of the patient to the CAR T cell therapy through various diagnostic tests and imaging procedures.
10
Continuously monitor the patient's condition and provide any necessary supportive care during the recovery phase.
Who needs car t cells over?
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CAR T cell therapy is primarily used to treat patients with certain types of cancer, particularly those who have not responded to traditional treatments such as surgery, chemotherapy, or radiation therapy.
02
It is commonly used in the treatment of hematologic malignancies like leukemia, lymphoma, and multiple myeloma.
03
CAR T cell therapy may also be considered for patients with solid tumors, although research in this area is still ongoing.
04
The decision to use CAR T cell therapy is made on a case-by-case basis by the patient's healthcare provider, taking into account various factors such as the type and stage of cancer, overall health, and treatment history.
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