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Guide to Using the BuprenorphineNaloxone (Suboxone) Microdosing Induction Method in Opioid Agonist Therapy (OAT) JULY 2023Guide to Using the BuprenorphineNaloxone (Suboxone) Microdosing Induction
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The microdosing induction method is a procedure used to introduce small, sub-threshold doses of a drug to patients, aiming to enhance tolerance and minimize side effects while determining effective dosage levels.
Researchers and organizations conducting clinical trials involving microdosing must file the microdosing induction method to ensure compliance with regulatory standards.
Filling out the microdosing induction method typically requires accurate documentation of the dosing regimen, participant information, adverse reactions, and outcomes observed during the trial.
The primary purpose of the microdosing induction method is to safely explore drug pharmacodynamics and pharmacokinetics, establish safety profiles, and potentially determine therapeutic efficacy without exposing participants to full doses.
Reports should include the drug administered, dosage levels, participant demographics, duration of the study, observed effects, and any adverse events encountered.
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