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UCLA UCLA Previously Published Works Title Pharmacogenetic Associations of Antipsychotic DrugRelated Weight Gain: A Systematic Review and Metaanalysis.Permalink https://escholarship.org/uc/item/5xh6b3pzJournal
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How to fill out cyp2d6 genetic variation and

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Obtain a DNA sample from the individual
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Perform a genetic test to identify the specific variations in the cyp2d6 gene
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Analyze the results to determine the individual's genetic variation status
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Interpret the results to understand how the individual may metabolize certain medications

Who needs cyp2d6 genetic variation and?

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Individuals who are prescribed medications that are metabolized by the CYP2D6 enzyme may benefit from genetic variation testing.
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Healthcare providers may also use this information to adjust dosage levels or choose alternative medications for patients with certain genetic variations.
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CYP2D6 genetic variation refers to the differences in the CYP2D6 gene, which encodes an enzyme involved in the metabolism of many drugs. These variations can affect how individuals respond to medication, influencing both efficacy and the risk of side effects.
Individuals undergoing pharmacogenomic testing due to specific medical conditions or those being prescribed medications that are significantly impacted by CYP2D6 metabolism may be required to file information regarding their CYP2D6 genetic variation.
To fill out the CYP2D6 genetic variation, one generally needs to provide personal and healthcare information, including the results from a genetic test that indicates the specific CYP2D6 variant(s) present.
The purpose of reporting CYP2D6 genetic variation is to guide personalized medication therapy, ensuring that patients receive the most effective drugs and dosages based on their genetic makeup.
The information that must be reported typically includes the specific variant alleles identified, the interpretation of the results (e.g., poor, intermediate, extensive, or ultra-rapid metabolizer), and any relevant clinical recommendations.
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