Get the free 2 - Guide A: Form 6 -- Daily Case Status Tracking ... - www2 cdc

Draft 2 - Guide A Form 6 -- Daily Case Status Tracking DRAFT Smallpox Daily Followup Sheet State Case ID Date Local Health Department Last Name First Name DOB Sex Hospital Chart No* Case Status Shaded area above is printed daily from existing surveillance data Current Status Updated Status Lab Status Epi Link Case Status Lab Status Epi Link Area above for updates.

Updated daily. Smallpox Smallpox is the most lethal virus known, with an incubation period in the range of 17 days to more than 90 days and a death rate of 90% to 99×. The WHO estimates that more than a million cases occur annually in endemic areas of more than 80 countries, including the United States, India, Pakistan and Saudi Arabia (1). In 2010, there were a total of 8,814 cases: 2,982 (53%) in high-prevalence areas, 1,918 (38%) in areas where sporadic cases were detected, but cases do not persist, and 1,913 (38%) during outbreaks (2). A large majority (92%) of reported cases were in Afghanistan, Pakistan, and Nigeria. (Table 2) In 2011, more than 50,000 people were living with the virus and the number of confirmed and probable cases surpassed 2 million (3). The number of laboratory-confirmed cases of disease from Pakistan and Nigeria totaled 1,982 and 1,920 respectively during the first 6 months of 2011. There have been five major disease outbreaks in Pakistan this year. In January, a highly pathogenic strain of smallpox was identified in Karachi. Since then, cases have caused an estimated 1,898 cases and 1,538 deaths (4). The most recent case to affect Pakistan occurred on 1 March, when five cases were reported on the outskirts of Peshawar, the country's largest city (5). The virus, initially detected using the polymerase chain reaction (PCR) method with a nucleic acid isolate, is a subtype B2 (Zaire) strain. This strain causes an approximately 90% fatality rate when tested in humans. In the past decade smallpox has been eradicated in all but one country. Since 1985, approximately 30 countries and several regions of Asia, Africa, and Latin America have been free of endemic disease. Smallpox is one of the most important biological weapons in the world, representing a significant strategic concern by many countries. The eradication effort in the 1980s and early 1990s led to an increasing role for the WHO. In 1985, the World Health Assembly adopted the Declaration of Stockholm with the United Nations General Assembly affirming the need for all countries to eliminate smallpox through vaccination.

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