Additional support was provided by grants K23 MH57396 and K21 MH49676 from the National Institute of Child Health and Human Development. (See Supplement II for additional details and supplemental tables.) References 1. Shuts CA, Tendon T, Moulton R, et al. Neonatal neuropathic pain is associated with developmental delay. Am J This Child 1994;150:1369-71.
2. Shuts CA, Tendon T, Moulton R. Behavioral outcome in a sibling birth cohort. Pediatrics 1998;100:17-22. Abstract
3. Decided J, Creswell C, Won M, et al. Genetic risk for postoperative analgesia-related pain is related to neuroplasticity in humans. Pain 2002;103:10-16.
4. Dearly CA, Guard AW, Shuts CA. Anesthesia and pain-related disorders in young children. Pediatrics 2000;107: E1. Abstract
5. Dearly CA, Guard AW, Shuts CA. Genetic and environmental influences on the onset of and their association with the outcome of postoperative analgesia-related pain. J Pain 2001;10:S5-S16. Abstract
6. Won MI, Won AH, Wang Y, Han S, Kim JR. Neonatal neuropsychology of anesthetic overdose. J Pain 2000;8:41-7. Abstract
7. Guard AW, Dearly CA, Shuts CA. Genetics and behavioral outcome following neonatal anesthesia: a case-control study. J Pain 2001;10:S9-S18. Abstract
8. O'Carroll KE, O'Carroll JM, Dearly CA, et al. Neonatal neuroanatomy of neonatal anesthetics and neonatal opioid administration. J Neuropathic Exp Neural 1992;53:835-50.
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10. Guard AW, Dearly CA, Smith WF, et al. Neonatal neuroanatomy: implications for neurobiological and behavioral impairment following neonatal anesthetic overdose. J Pain 1993;4:5. Abstract
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Early Childhood Exposure to Anesthesia and Risk of Developmental and Behavioral Disorders in a Sibling Birth Cohort Charles DiMaggio, PhD×, Lena S. Sun, MD×, Group Li, MD, DPH * Corresponding Author:
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