Other information Manufacturer Wyeth Diagnostics, Inc. URL
The anti-SLC39A4 antibody ab90574 is the second SLC39A4 anti-receptor antibody. Ab90574 (3) has the same structural and functional properties as islet-specific SLC39A4-1 antibody ab90574 1; however, it is non-competitive and does not interact with SLC39A4-2. This SLC39A4 anti-MHC complex has been proposed as an additional diagnostic marker (1). The antibody is also a substrate for the anti-MHC complex formed between monocles and macrophages (16). The antibody ab90574 1 is the preferred antibody used to detect non-specific SLC39A4 antibodies in the presence of MHC-associated monocle antibodies and macrophages antibodies, whereas the antibody ab90574 2 detects SLC39A4 in association with MHC-specific antibodies, which have not been detected by the antibody ab90574 1.
The anti-SLC39A4 antibody ab90576 is an immunochemical assay that uses synthetic peptide sequence corresponding to a region within internal sequence amino acids 360-409 in the MHC region of human SLC39A4 to test for non-specific antibodies to SLC39A4 (18). To date, this test has been applied only to detect monocle MHC-A1 and non-monocyte MHC-A2 antibodies and to correlate SLC39-A4 cross-reactivity with monocle or macrophages antibody activity. A single dose of the anti-SLC39A4 antibody ab90576 1/glycosylated human plasma (HPL) conjugate (ABT-2G00) was applied to 96 healthy volunteers (n = 10/group). The anti-SLC39A4-1 antibody was immunostained with a secondary antibody conjugated to polyamide and incubation was for 1 h at 37 C. The intraperitoneal (i.p.) injection of recombinant SLC39A4 (SLC39C-I) and human CD8 + T cells (hCD8 T cells/mL) was performed as described (18, 19).
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Anti-SLC39A4 antibody ab90076 1 Product Data sheet 1 Overview Product name Anti-SLC39A4 antibody Description Rabbit polyclonal to SLC39A4 Tested applications WB Cross reactivity Reacts with: Human
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What is anti-slc39a4 antibody ab90076?
Anti-slc39a4 antibody ab90076 is a specific type of antibody that targets the protein encoded by the slc39a4 gene.
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There is no specific requirement for filing anti-slc39a4 antibody ab90076. It is commonly used in research and biomedical laboratories.
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What is the purpose of anti-slc39a4 antibody ab90076?
The purpose of anti-slc39a4 antibody ab90076 is to specifically bind to the slc39a4 protein and facilitate its detection or manipulation in experimental settings.
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The specific information required for reporting anti-slc39a4 antibody ab90076 depends on the regulatory guidelines or publication requirements. Generally, it includes antibody details, experimental methods, and results.
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