Get the free New health 0102. Form 29B - 21102010 (Aberdeen)

My A10 Monday, February 1, 2010, HEALTH Diarrhea vaccines could save two million lives By Maggie Fox WASHINGTON: Vaccines against rotavirus, which can kills babies and young children within days by

The World Health Organization said it will consider making the vaccines available for countries in West and Central Africa, where the disease kills about one child every 25 seconds. The vaccination rate was about 30 per cent in the two studies. “There's no question these vaccines would be important here because the disease is so deadly,” said David Katz, an infectious disease expert at Columbia University, who was not involved in either study. About half of all children worldwide get diarrhea at least once at least once each year. The main treatment is water treatment, Katz noted, but often that isn't fast enough. The WHO estimates up to 200 million children worldwide suffer from diarrhea, causing 2.2 million to 5.6 million child deaths per year. “We are looking at thousands of millions of years of human history,” Katz said. About 585-million vaccine doses have already been sold in Africa, Asia and Latin America. In the developed world, the U.S. Food and Drug Administration recently approved the Rotate injection, which is given a few hours after a kid has eaten or drunk contaminated food or drinks. Children should get three rotavirus injections every 30 months. The vaccine is being made by GSK Vaccine. The Rotate vaccine is manufactured by Medicine, and it should be available in the U.S. by the end of 2010. WHO experts said the combination Tap vaccine would have the most impact in Kenya, which has the highest child death figures from rotavirus globally. About 40 million children worldwide now have immunity to the strain of rotavirus that killed three-year-old Abubakar in Kenya in 1998 and killed two-year-old Al-Zuhaira in Sudan in 1999. WHO hopes to make rotavirus vaccine available to about 90 per cent of children in developing countries as soon as possible, but that would require additional research and development in the rest. WHO officials cited one study that showed the combination vaccine reduced the chance of death from rotavirus by 30 per cent. “This is a great moment because rotavirus causes a tremendous amount of death,” said Dr. Peter Hotel, who is leading the Rotate vaccine research at the WHO in Geneva. “It's a major health problem.” There are several other rotavirus vaccines that have been shown to have high efficacy against rotaviruses in animals and were used in the Tap vaccination program, Katz said.

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