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The Journal of Neuroscience, July 20, 2016 36(29):77277739 7727Neurobiology of DiseaseGlutamateMediated Blood Brain Barrier Opening: Implications for Neuroprotective and Drug Delivery Audi Azana,1,2,3*
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To fill out glutamate-mediated bloodbrain barrier opening, follow these steps:
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Start by preparing a solution of glutamate at a concentration of 1-10 mM.
03
Using a syringe, inject the glutamate solution into the target area of the brain.
04
Allow sufficient time for the glutamate to diffuse and interact with the bloodbrain barrier.
05
Monitor the opening of the bloodbrain barrier by measuring changes in permeability or using imaging techniques.
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Once the desired level of bloodbrain barrier opening is achieved, you can proceed with your intended research or treatment.

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Glutamate-mediated bloodbrain barrier opening is often needed in certain research and therapeutic applications.
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Here are some examples of who may need this procedure:
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- Researchers studying brain disorders and the delivery of drugs to the brain.
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- Medical professionals developing new treatment strategies for neurological conditions.
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- Patients with certain brain diseases or tumors requiring targeted drug delivery.
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- Scientists investigating the transport of molecules across the bloodbrain barrier.
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It is important to consult with experts in the field before considering glutamate-mediated bloodbrain barrier opening.

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