Blood tested for HER2, estrogen receptor, and progesterone receptors was analyzed for glycosylation status and levels of serum total and free estrogen, progesterone, and RHEAS as well as total lipid profiles. Herceptin, a HER2 related antibody, was examined in patients with HER2 status unknown and in all women with HER2 positive cancer and in those without documented HER2 status. Results: A statistically significant difference in glycosylation status, mean serum testosterone levels, and mean serum SBG levels was noted between HER2 positive patients with known risk versus unknown risk for breast cancer (p less than 0.05 with all analyzes, see Tables 5 and 6). There appeared to be a negative association between blood type and serum Total cholesterol, cholesterol/ HDL, and triglyceride levels. In all patients with a single blood type blood, serum total cholesterol and triglyceride levels were significantly higher with an HER2 positivity versus unknown risk (p less than 0.05).
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Clinical Medicine & Research Volume 9, Number 3/4: 111-118 2011 Marsh field Clinic clinkers.org Original Research Blood Type, Hormone Receptor Status, HER2/new Status, and Survival in Breast Cancer:
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