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De Nova sequencing refers to sequencing a novel genome where there is no reference sequence available for alignment. Sequence reads are assembled as configs, and the coverage quality of de Nova sequence data depends on the size and continuity of the configs (i.e., the number of gaps in the data).
The genome assembly is simply the genome sequence produced after chromosomes have been fragmented, those fragments have been sequenced, and the resulting sequences have been put back together. ... Each species in Ensemble has a reference genome assembly that is produced by an international genome consortium.
The genome assembly is simply the genome sequence produced after chromosomes have been fragmented, those fragments have been sequenced, and the resulting sequences have been put back together. ... Each species in Ensemble has a reference genome assembly that is produced by an international genome consortium.
In bioinformatics, sequence assembly refers to aligning and merging fragments from a longer DNA sequence in order to reconstruct the original sequence. ... Typically, the short fragments, called reads, result from shotgun sequencing genomic DNA, or gene transcript (EST's).
Velvet De Novo Assembly and Polka Genome Annotation Push-button de Nova assembly pipeline for bacterial samples, for rapid annotation of genes and identification of coding regions. Assemble.
Most genes contain the information needed to make functional molecules called proteins. (A few genes produce other molecules that help the cell assemble proteins.) The journey from gene to protein is complex and tightly controlled within each cell.
A config (from contiguous) is a set of overlapping DNA segments that together represent a consensus region of DNA.
Config maps are important because they provide the ability to study a complete, and often large, segment of the genome by examining a series of overlapping clones which then provide an unbroken succession of information about that region.
Scaffold: 1. In genetics, the chromosome structure consisting entirely of Johnstone proteins remaining after all the DNA and histone proteins have been removed from a chromosome. 2. In genomic mapping, a series of configs that are in the right order but not necessarily connected in one continuous stretch of sequence.
In order to make it easier to talk about our data gained by the shotgun method of sequencing we have invented the word “config”. A config is a set of gel readings that are related to one another by overlap of their sequences. ... This defines a config to be a set of overlapping segments of DNA.
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